About Me
Data scientist, specialised in genomics and bioinformatics.
Experiences
Research Officer (Bioinformatician)
2022 - Present · QIMR Berghofer Medical Research Institute
- Develop pipelines for mutation detection using long read sequencing.
- Benchmark bioinformatic tools using cell lines and clinical sampels.
- Analysis mutational signatures and HRD prediction using machine learning classification models.
Research Assistant (Bioinformatician)
2018 - 2019 · ARC Centre of Excellence for Coral Reef Studies, James Cook University
Education
Ph.D. in Bioinformatics
2019 - 2023 · James Cook University
Thesis: Exploiting whole-genome sequencing to understand the evolution of corals and their symbionts.
M.S. in Genetics
2014 - 2017 · Chinese Academy of Sciences
Thesis: De novo genome research of ocellaris clownfish based on next-generation sequencing
B.S. in Bioenigineering
2010 - 2014 · Sichuan Agricultural University
Publications
Journal Articles
2025. Integrating breast tumor homologous recombination deficiency status to aid germline BRCA1 and BRCA2 variant classification. eBiomedicine.
2024. Performance of somatic structural variant calling in lung cancer using Oxford Nanopore sequencing technology. BMC Genomics.
2024. Chromosomal inversions harbour excess mutational load in the coral, Acropora kenti, on the Great Barrier Reef. Molecular Ecology.
2023. STING activation promotes autologous type I interferon-dependent development of type 1 regulatory T cells during malaria. Journal of Clinical Investigation.
2022. Evolutionary responses of a reef-building coral to climate change at the end of the last glacial maximum. Molecular Biology and Evolution.
2022. DMSP Production by Coral-Associated Bacteria. Frontiers in Marine Science.
2021. Phenotypic and genomic adaptations to the extremely high elevation in plateau zokor (Myospalax baileyi). Molecular Ecology.
2021. Phylogenomic relationships and molecular convergences to subterranean life in rodent family Spalacidae. Zoological Research.
2020. Genomic signatures in the coral holobiont reveal host adaptations driven by Holocene climate change and reef specific symbionts. Science Advances.
2020. Comparative transcriptomic analyses of Chromera and Symbiodiniaceae. Environmental Microbiology Reports.
2018. Shotgun Proteomics Analysis of Saliva and Salivary Gland Tissue from the Common Octopus Octopus vulgaris. Journal of Proteome Research.
Projects
Skills
Python, RShell script, SQLHTML, CSS, JavascriptGit, Containerization, CI & CDHobbies
- Gaming
- Running
- Reading